Amended Protocol Ver. 1.4 Developed By Icmr For Covid 19 Patients Treatment Through The Convalescent Plasma
The novel coronavirus that started in Wuhan, China in December 2019, had quickly been declared as a pandemic by the World Health Organization. It is caused by severe acute respiratory syndrome coronavirus 2 and has resulted in millions of cases and deaths all over the world. Some of the clinical manifestations of Covid 19 include fever, fatigue, and cough, shortness of breath along with some of the less common symptoms like headache, diarrhoea and nausea. Along with several irregularities of parameters in the body, hypoxia-induced thrombosis enhances blood viscosity as well as hypoxia-induced transcription factor-dependent signaling pathway. Covid-19 also attacks the beta chain of hemoglobin for iron dissociation to make porphyrin. This decreases the lungs ability to exchange oxygen and carbon dioxide that results in ground-glass opacities. Till now there are no certain treatment methods for Covid-19 and several trials are being made all over the world to study the efficiency o